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Influenza A Virus Pre-Infection Exacerbates Pseudomonas aeruginosa-Mediated Lung Damage Through Increased MMP-9 Expression, Decreased Elafin Production and Tissue Resilience

Individuals with impaired immune responses, such as ventilated and cystic fibrosis patients are often infected with Pseudomonas aeruginosa (P.a) bacteria, and a co-infection with the Influenza virus (IAV) is often present. It has been known for many years that infection with IAV predisposes the host...

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Detalles Bibliográficos
Autores principales: Villeret, Berengère, Solhonne, Brigitte, Straube, Marjolène, Lemaire, Flora, Cazes, Aurélie, Garcia-Verdugo, Ignacio, Sallenave, Jean-Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031978/
https://www.ncbi.nlm.nih.gov/pubmed/32117268
http://dx.doi.org/10.3389/fimmu.2020.00117