Cargando…
Influenza A Virus Pre-Infection Exacerbates Pseudomonas aeruginosa-Mediated Lung Damage Through Increased MMP-9 Expression, Decreased Elafin Production and Tissue Resilience
Individuals with impaired immune responses, such as ventilated and cystic fibrosis patients are often infected with Pseudomonas aeruginosa (P.a) bacteria, and a co-infection with the Influenza virus (IAV) is often present. It has been known for many years that infection with IAV predisposes the host...
Autores principales: | Villeret, Berengère, Solhonne, Brigitte, Straube, Marjolène, Lemaire, Flora, Cazes, Aurélie, Garcia-Verdugo, Ignacio, Sallenave, Jean-Michel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7031978/ https://www.ncbi.nlm.nih.gov/pubmed/32117268 http://dx.doi.org/10.3389/fimmu.2020.00117 |
Ejemplares similares
-
IL-6-elafin genetically modified macrophages as a lung immunotherapeutic strategy against Pseudomonas aeruginosa infections
por: Kheir, Saadé, et al.
Publicado: (2022) -
Pseudomonas aeruginosa LasB protease impairs innate immunity in mice and humans by targeting a lung epithelial cystic fibrosis transmembrane regulator–IL-6–antimicrobial–repair pathway
por: Saint-Criq, Vinciane, et al.
Publicado: (2018) -
The antimicrobial molecule trappin-2/elafin has anti-parasitic properties and is protective in vivo in a murine model of cerebral malaria
por: Roussilhon, Christian, et al.
Publicado: (2017) -
Pseudomonas Aeruginosa Lung Infection Subverts Lymphocytic Responses through IL-23 and IL-22 Post-Transcriptional Regulation
por: Villeret, Bérengère, et al.
Publicado: (2022) -
Acute exposure to silica nanoparticles enhances mortality and increases lung permeability in a mouse model of Pseudomonas aeruginosa pneumonia
por: Delaval, Mathilde, et al.
Publicado: (2015)