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Intracellular distribution and internalization pathways of guanidinylated bioresponsive poly(amido amine)s in gene delivery()
Guanidinylated bioresponsive poly(amido amine)s polymers, CAR-CBA and CHL-CBA, were synthesized by Michael-type addition reaction between guanidine hydrochloride (CAR) or chlorhexidine (CHL) and N,N′-cystaminebisacrylamide (CBA). Previous studies have shown that both polymers had high transfection e...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shenyang Pharmaceutical University
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032094/ https://www.ncbi.nlm.nih.gov/pubmed/32104410 http://dx.doi.org/10.1016/j.ajps.2018.02.008 |