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Intracellular distribution and internalization pathways of guanidinylated bioresponsive poly(amido amine)s in gene delivery()

Guanidinylated bioresponsive poly(amido amine)s polymers, CAR-CBA and CHL-CBA, were synthesized by Michael-type addition reaction between guanidine hydrochloride (CAR) or chlorhexidine (CHL) and N,N′-cystaminebisacrylamide (CBA). Previous studies have shown that both polymers had high transfection e...

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Detalles Bibliográficos
Autores principales: Zhang, Jinmin, Wang, Chunxi, Lu, Mei, Xing, Haonan, Yang, Tianzhi, Cai, Cuifang, Zhao, Xiaoyun, Wei, Minjie, Yu, Jiankun, Ding, Pingtian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032094/
https://www.ncbi.nlm.nih.gov/pubmed/32104410
http://dx.doi.org/10.1016/j.ajps.2018.02.008