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Formulation optimization of scutellarin-loaded HP-β-CD/chitosan nanoparticles using response surface methodology with Box–Behnken design
The aim of this paper is to investigate and optimize the preparation of scutellarin (SCU)-loaded HP-β-CD/chitosan (CS) nanoparticles (CD/CS-SCU-NPs). CD/CS-SCU-NPs were prepared by ionic cross-linking method and the process and formulation variables were optimized using response surface methodology...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shenyang Pharmaceutical University
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032107/ https://www.ncbi.nlm.nih.gov/pubmed/32104349 http://dx.doi.org/10.1016/j.ajps.2017.04.003 |