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Extended tacrolimus release via the combination of lipid-based solid dispersion and HPMC hydrogel matrix tablets

The objective of this study is to evaluate the feasibility of obtaining extended release of tacrolimus by a novel combination of lipid-based solid dispersion and matrix-type extended release tablet techniques. Tacrolimus solid dispersion was prepared using glycerylbehenate (Compritol(®) ATO888) and...

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Detalles Bibliográficos
Autores principales: Xu, Hui, Liu, Li, Li, Xuehui, Ma, Junyuan, Liu, Rui, Wang, Shaoning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032121/
https://www.ncbi.nlm.nih.gov/pubmed/32104473
http://dx.doi.org/10.1016/j.ajps.2018.08.001