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Preparation, characterization and in vivo evaluation of alginate-coated chitosan and trimethylchitosan nanoparticles loaded with PR8 influenza virus for nasal immunization

For efficient mucosal vaccine delivery, nanoparticulate antigens are better taken by microfold cells in the nasal associated lymphoid tissue and also dendritic cells. Nanoparticles based on polymers such as chitosan (CHT) and its water soluble derivative, trimethylchitosan (TMC), could be successful...

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Detalles Bibliográficos
Autores principales: Mosafer, Jafar, Sabbaghi, Amir-Hossein, Badiee, Ali, Dehghan, Solmaz, Tafaghodi, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032123/
https://www.ncbi.nlm.nih.gov/pubmed/32104453
http://dx.doi.org/10.1016/j.ajps.2018.04.005