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Biorelevant test for supersaturable formulation

Supersaturable formulation can generate supersaturation after dissolution, providing kinetic advantage in vivo. However, the supersaturation may precipitate before being absorbed, which makes it difficult to ensure and predict its in vivo performance. The traditional USP method is typically for Qual...

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Detalles Bibliográficos
Autores principales: Lu, Enxian, Li, Shoufeng, Wang, Zhongqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032141/
https://www.ncbi.nlm.nih.gov/pubmed/32104309
http://dx.doi.org/10.1016/j.ajps.2016.10.002