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Biorelevant test for supersaturable formulation
Supersaturable formulation can generate supersaturation after dissolution, providing kinetic advantage in vivo. However, the supersaturation may precipitate before being absorbed, which makes it difficult to ensure and predict its in vivo performance. The traditional USP method is typically for Qual...
Autores principales: | Lu, Enxian, Li, Shoufeng, Wang, Zhongqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shenyang Pharmaceutical University
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032141/ https://www.ncbi.nlm.nih.gov/pubmed/32104309 http://dx.doi.org/10.1016/j.ajps.2016.10.002 |
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