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Virtual population pharmacokinetic using physiologically based pharmacokinetic model for evaluating bioequivalence of oral lacidipine formulations in dogs

The aim of the present study was to investigate virtual population pharmacokinetic using physiologically based pharmacokinetic (PBPK) model for evaluating bioequivalence of oral lacidipine formulations in dogs. The dissolution behaviors of three lacidipine formulations including one commercial produ...

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Detalles Bibliográficos
Autores principales: Yang, Bin, Wu, Chunnuan, Ji, Bin, Wu, Mingrui, He, Zhonggui, Shang, Lei, Sun, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032150/
https://www.ncbi.nlm.nih.gov/pubmed/32104318
http://dx.doi.org/10.1016/j.ajps.2016.03.003