Cooperative effect of polyvinylpyrrolidone and HPMC E5 on dissolution and bioavailability of nimodipine solid dispersions and tablets

Solid dispersion (SD) systems have been extensively used to increase the dissolution and bioavailability of poorly water-soluble drugs. To circumvent the limitations of polyvinylpyrrolidone (PVP) dispersions, HPMC E5 was applied in the formulation process and scaling-up techniques, simultaneously. I...

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Detalles Bibliográficos
Autores principales: Sun, Zhisu, Zhang, Huicong, He, Huiyang, Sun, Lingling, Zhang, Xiaorui, Wang, Qun, Li, Kexin, He, Zhonggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032151/
https://www.ncbi.nlm.nih.gov/pubmed/32104493
http://dx.doi.org/10.1016/j.ajps.2018.08.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032151/
https://www.ncbi.nlm.nih.gov/pubmed/32104493
http://dx.doi.org/10.1016/j.ajps.2018.08.005

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