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Preparation and in vitro-in vivo evaluation of intestinal retention pellets of Berberine chloride to enhance hypoglycemic and lipid-lowing efficacy

Berberine chloride (BBR) is a pharmacokinetic profile of drug with poor bioavailability but good therapeutic efficacy, which is closely related to the discovery of BBR intestinal target. The major aim of this paper is to develop BBR intestinal retention type sustained-release pellets and evaluate th...

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Detalles Bibliográficos
Autores principales: Li, Guofei, Zhao, Mingming, Su, Xianying, Song, Lin, Zhao, Limei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032169/
https://www.ncbi.nlm.nih.gov/pubmed/32104483
http://dx.doi.org/10.1016/j.ajps.2018.09.006