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Polymeric nanoparticles developed by vitamin E-modified aliphatic polycarbonate polymer to promote oral absorption of oleanolic acid

Oleanolic acid (OA) exhibited good pharmacological activities in the clinical treatment of hypoglycemia, immune regulation, acute jaundice and chronic toxic hepatitis. However, the oral delivery of OA is greatly limited by its inferior water solubility and poor intestinal mucosa permeability. Herein...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjuan, Liang, Chufan, Liu, Hao, Li, Zhenbao, Chen, Rui, Zhou, Mei, Li, Dan, Ye, Qing, Luo, Cong, Sun, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032188/
https://www.ncbi.nlm.nih.gov/pubmed/32104372
http://dx.doi.org/10.1016/j.ajps.2017.08.003