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Polymeric nanoparticles developed by vitamin E-modified aliphatic polycarbonate polymer to promote oral absorption of oleanolic acid
Oleanolic acid (OA) exhibited good pharmacological activities in the clinical treatment of hypoglycemia, immune regulation, acute jaundice and chronic toxic hepatitis. However, the oral delivery of OA is greatly limited by its inferior water solubility and poor intestinal mucosa permeability. Herein...
Autores principales: | Zhang, Wenjuan, Liang, Chufan, Liu, Hao, Li, Zhenbao, Chen, Rui, Zhou, Mei, Li, Dan, Ye, Qing, Luo, Cong, Sun, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shenyang Pharmaceutical University
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032188/ https://www.ncbi.nlm.nih.gov/pubmed/32104372 http://dx.doi.org/10.1016/j.ajps.2017.08.003 |
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