Synthesis and evaluation of cationic polymeric micelles as carriers of lumbrokinase for targeted thrombolysis

To achieve targeted thrombolysis, a targeted delivery system of lumbrokinase (LK) was constructed using RGDfk-conjugated hybrid micelles. Based on the specific affinity of RGDfk to glycoprotein complex of GPⅡb/Ⅲa expressed on the surface of membrane of activated platelet, LK loaded targeted micelles...

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Detalles Bibliográficos
Autores principales: Pan, Yang, Wang, Xiahui, Yin, Zongning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032199/
https://www.ncbi.nlm.nih.gov/pubmed/32104446
http://dx.doi.org/10.1016/j.ajps.2018.03.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032199/
https://www.ncbi.nlm.nih.gov/pubmed/32104446
http://dx.doi.org/10.1016/j.ajps.2018.03.004

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