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Synthesis and evaluation of cationic polymeric micelles as carriers of lumbrokinase for targeted thrombolysis
To achieve targeted thrombolysis, a targeted delivery system of lumbrokinase (LK) was constructed using RGDfk-conjugated hybrid micelles. Based on the specific affinity of RGDfk to glycoprotein complex of GPⅡb/Ⅲa expressed on the surface of membrane of activated platelet, LK loaded targeted micelles...
Autores principales: | Pan, Yang, Wang, Xiahui, Yin, Zongning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shenyang Pharmaceutical University
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032199/ https://www.ncbi.nlm.nih.gov/pubmed/32104446 http://dx.doi.org/10.1016/j.ajps.2018.03.004 |
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