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Integration of phospholipid-drug complex into self-nanoemulsifying drug delivery system to facilitate oral delivery of paclitaxel

Self-nanoemulsifying drug delivery system (SNEDDS) has emerged as a promising platform to improve oral absorption of drugs with poor solubility and low permeability. However, large polarity molecules with insufficient lipid solubility, such as paclitaxel (PTX), would suffer from inferior formulation...

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Detalles Bibliográficos
Autores principales: Ding, Dawei, Sun, Bingjun, Cui, Weiping, Chen, Qin, Zhang, Xuanbo, Zhang, Haotian, He, Zhonggui, Sun, Jin, Luo, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032203/
https://www.ncbi.nlm.nih.gov/pubmed/32104482
http://dx.doi.org/10.1016/j.ajps.2018.10.003