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A nano-cocrystal strategy to improve the dissolution rate and oral bioavailability of baicalein

Baicalein (BE) is one of the main active flavonoids representing the variety of pharmacological effects including anticancer, anti-inflammatory and cardiovascular protective activities, but it's very low solubility, dissolution rate and poor oral absorption limit the therapeutic applications. I...

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Detalles Bibliográficos
Autores principales: Pi, Jiaxin, Wang, Shuya, Li, Wen, Kebebe, Dereje, Zhang, Ying, Zhang, Bing, Qi, Dongli, Guo, Pan, Li, Nan, Liu, Zhidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032205/
https://www.ncbi.nlm.nih.gov/pubmed/32104447
http://dx.doi.org/10.1016/j.ajps.2018.04.009