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A nano-cocrystal strategy to improve the dissolution rate and oral bioavailability of baicalein
Baicalein (BE) is one of the main active flavonoids representing the variety of pharmacological effects including anticancer, anti-inflammatory and cardiovascular protective activities, but it's very low solubility, dissolution rate and poor oral absorption limit the therapeutic applications. I...
Autores principales: | Pi, Jiaxin, Wang, Shuya, Li, Wen, Kebebe, Dereje, Zhang, Ying, Zhang, Bing, Qi, Dongli, Guo, Pan, Li, Nan, Liu, Zhidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shenyang Pharmaceutical University
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032205/ https://www.ncbi.nlm.nih.gov/pubmed/32104447 http://dx.doi.org/10.1016/j.ajps.2018.04.009 |
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