Piperacillin enhances the inhibitory effect of tazobactam on β-lactamase through inhibition of organic anion transporter 1/3 in rats

To assess the mechanism of the pharmacokinetic interaction between piperacillin and tazobactam, renal excretion and pharmacokinetic studies of piperacillin/tazobactam were investigated in normal and bacteremia rats. A bacteremia model was established to investigate the pharmacokinetic properties of...

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Detalles Bibliográficos
Autores principales: Yang, Shilei, Liu, Zhihao, Wang, Changyuan, Wen, Shijie, Meng, Qiang, Huo, Xiaokui, Sun, Huijun, Ma, Xiaodong, Peng, Jinyong, He, Zhonggui, Liu, Kexin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032209/
https://www.ncbi.nlm.nih.gov/pubmed/32104494
http://dx.doi.org/10.1016/j.ajps.2018.11.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032209/
https://www.ncbi.nlm.nih.gov/pubmed/32104494
http://dx.doi.org/10.1016/j.ajps.2018.11.003

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