Systematically optimized topical delivery system for Loperamide hydrochloride: Formulation design, in vitro and in vivo biopharmaceutical evaluation

This study aimed to develop a suitable topical delivery system containing diethylene glycol monoethyl ether (DGME) for Loperamide hydrochloride (Lop). Two factors, three levels Central-Composite design were applied by generating a quadratic polynomial equation to form contour plots and response surf...

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Detalles Bibliográficos
Autores principales: Shu, Jianhui, Zhao, Jingjing, Guo, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032216/
https://www.ncbi.nlm.nih.gov/pubmed/32104399
http://dx.doi.org/10.1016/j.ajps.2017.08.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032216/
https://www.ncbi.nlm.nih.gov/pubmed/32104399
http://dx.doi.org/10.1016/j.ajps.2017.08.009

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