Continuous melt granulation to develop high drug loaded sustained release tablet of Metformin HCl

The present work explores the application of melt granulation technology to develop a high drug loaded sustained release matrix tablet of Metformin HCl using hydroxypropylcellulose (HPC) as a hydrophilic binder and stearic acid as an extrusion aid for producing cohesive granules. This novel approach...

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Detalles Bibliográficos
Autores principales: Vaingankar, Pradnya, Amin, Purnima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032224/
https://www.ncbi.nlm.nih.gov/pubmed/32104312
http://dx.doi.org/10.1016/j.ajps.2016.08.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032224/
https://www.ncbi.nlm.nih.gov/pubmed/32104312
http://dx.doi.org/10.1016/j.ajps.2016.08.005

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