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Modulating intestinal mucus barrier for nanoparticles penetration by surfactants

Improving peroral delivery efficiency is always a persistent goal for both small-molecule and macromolecular drug development. However, intestinal mucus barrier which greatly impedes drug-loaded nanoparticles penetration is commonly overlooked. Therefore, in this study, taking fluorescent labeled PL...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Dong, Wei, Cheng, Hongbo, Zhang, Meixia, Kou, Yongqiang, Guan, Jian, Liu, Qiaoyu, Gao, Mingyue, Wang, Xiuhua, Mao, Shirui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032225/
https://www.ncbi.nlm.nih.gov/pubmed/32104481
http://dx.doi.org/10.1016/j.ajps.2018.09.002