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Triphenylphosphonium-modified mitochondria-targeted paclitaxel nanocrystals for overcoming multidrug resistance

Mitochondria are currently known as novel targets for treating cancer, especially for tumors displaying multidrug resistance (MDR). This present study aimed to develop a mitochondria-targeted delivery system by using triphenylphosphonium cation (TPP(+))-conjugated Brij 98 as the functional stabilize...

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Detalles Bibliográficos
Autores principales: Han, Xue, Su, Ruijuan, Huang, Xiuqing, Wang, Yingli, Kuang, Xiao, Zhou, Shuang, Liu, Hongzhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032231/
https://www.ncbi.nlm.nih.gov/pubmed/32104484
http://dx.doi.org/10.1016/j.ajps.2018.06.006