Cargando…

Triphenylphosphonium-modified mitochondria-targeted paclitaxel nanocrystals for overcoming multidrug resistance

Mitochondria are currently known as novel targets for treating cancer, especially for tumors displaying multidrug resistance (MDR). This present study aimed to develop a mitochondria-targeted delivery system by using triphenylphosphonium cation (TPP(+))-conjugated Brij 98 as the functional stabilize...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Xue, Su, Ruijuan, Huang, Xiuqing, Wang, Yingli, Kuang, Xiao, Zhou, Shuang, Liu, Hongzhuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shenyang Pharmaceutical University 2019
Materias:	Original Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032231/ https://www.ncbi.nlm.nih.gov/pubmed/32104484 http://dx.doi.org/10.1016/j.ajps.2018.06.006

Ejemplares similares

Synthesis of triphenylphosphonium vitamin E derivatives as mitochondria-targeted antioxidants
por: Jameson, Victoria J.A., et al.
Publicado: (2015)

Effective magnetic hyperthermia induced by mitochondria‐targeted nanoparticles modified with triphenylphosphonium‐containing phospholipid polymers
por: Kaneko, Masahiro, et al.
Publicado: (2023)

Mitochondria-targeted alginate/triphenylphosphonium-grafted-chitosan for treatment of hepatocellular carcinoma
por: Arafa, Kholoud K., et al.
Publicado: (2022)

Efflux pump-mediated resistance to antifungal compounds can be prevented by conjugation with triphenylphosphonium cation
por: Chang, Wenqiang, et al.
Publicado: (2018)

Mitochondria-targeted triphenylphosphonium-based compounds do not affect estrogen receptor α
por: Zinovkina, Ludmila A., et al.
Publicado: (2020)

Tumor acidity activated triphenylphosphonium-based mitochondrial targeting nanocarriers for overcoming drug resistance of cancer therapy
por: Yu, Hui, et al.
Publicado: (2019)

Indomethacin-based stimuli-responsive micelles combined with paclitaxel to overcome multidrug resistance
por: Wang, Shuanghu, et al.
Publicado: (2017)

Stability of Phenyl-Modified Triphenylphosphonium Conjugates and Interactions with DTPA
por: Gruenwald, Hannah K., et al.
Publicado: (2022)

In Vitro Effect of Mitochondria-Targeted Triphenylphosphonium-Based Compounds (Honokiol, Lonidamine, and Atovaquone) on the Platelet Function and Cytotoxic Activity
por: Montecino-Garrido, Héctor, et al.
Publicado: (2022)

A simple reduction-sensitive micelles co-delivery of paclitaxel and dasatinib to overcome tumor multidrug resistance
por: Li, Jun, et al.
Publicado: (2017)

Adjudin-loaded redox-sensitive paclitaxel-prodrug micelles for overcoming multidrug resistance with efficient targeted Colon cancer therapy
por: Chen, Deli, et al.
Publicado: (2020)

Membrane-Targeting Triphenylphosphonium Functionalized Ciprofloxacin for Methicillin-Resistant Staphylococcus aureus (MRSA)
por: Kang, Sangrim, et al.
Publicado: (2020)

Nanopreparations for mitochondria targeting drug delivery system: Current strategies and future prospective
por: Wang, Zhenjie, et al.
Publicado: (2017)

pH-activated, mitochondria-targeted, and redox-responsive delivery of paclitaxel nanomicelles to overcome drug resistance and suppress metastasis in lung cancer
por: Wang, He, et al.
Publicado: (2021)

(Furfurylamino)triphenylphosphonium bromide
por: Martínez de León, Carla, et al.
Publicado: (2012)

Crystal structure of triphenylphosphoniummethylenetrifluoroborate
por: Bateman, Christopher M., et al.
Publicado: (2017)

Overcoming drug efflux-based multidrug resistance in cancer with nanotechnology
por: Xue, Xue, et al.
Publicado: (2012)

Penfluridol overcomes paclitaxel resistance in metastatic breast cancer
por: Gupta, Nehal, et al.
Publicado: (2019)

Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells
por: Jiménez-Guerrero, Rocío, et al.
Publicado: (2018)

pH-triggered surface charge-switchable polymer micelles for the co-delivery of paclitaxel/disulfiram and overcoming multidrug resistance in cancer
por: Huo, Qiang, et al.
Publicado: (2017)

An Antimitotic and Antivascular Agent BPR0L075 Overcomes Multidrug Resistance and Induces Mitotic Catastrophe in Paclitaxel-Resistant Ovarian Cancer Cells
por: Wang, Xiaolei, et al.
Publicado: (2013)

(Cyanomethyl)triphenylphosphonium chloride
por: Shafiq, Muhammad, et al.
Publicado: (2008)

Novel Gallate Triphenylphosphonium Derivatives with Potent Antichagasic Activity
por: Cortes, Leonel A., et al.
Publicado: (2015)

Synthesis and Antiproliferative Activity of Triphenylphosphonium Derivatives of Natural Allylpolyalkoxybenzenes
por: Tsyganov, Dmitry V., et al.
Publicado: (2022)

Overcoming Multidrug Resistance in Cancer Stem Cells
por: Moitra, Karobi
Publicado: (2015)

Pharmacological Strategies for Overcoming Multidrug Resistance to Chemotherapy
por: Fedotcheva, T. A., et al.
Publicado: (2023)

Green Tea Catechin-Based Complex Micelles Combined with Doxorubicin to Overcome Cardiotoxicity and Multidrug Resistance
por: Cheng, Tangjian, et al.
Publicado: (2016)

Triphenylphosphonium Modified Mesoporous Silica Nanoparticle for Enhanced Algicidal Efficacy of Cyclohexyl-(3,4-dichlorobenzyl) Amine
por: Kim, Ho-Joong, et al.
Publicado: (2022)

Cancer Stem Cells as a Potential Target to Overcome Multidrug Resistance
por: Cho, Yena, et al.
Publicado: (2020)

Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity
por: Millard, Melissa, et al.
Publicado: (2010)

Docking study of triphenylphosphonium cations as estrogen receptor α modulators
por: Salisbury, Joseph P, et al.
Publicado: (2009)

(3-Chloropropyl)triphenylphosphonium bromide
por: Kavitha, Channappa N., et al.
Publicado: (2012)

Mitochondriotropic and Cardioprotective Effects of Triphenylphosphonium-Conjugated Derivatives of the Diterpenoid Isosteviol
por: Testai, Lara, et al.
Publicado: (2017)

Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome
por: Chen, Chih-Wei, et al.
Publicado: (2021)

Quantitative Proteomics Analysis Identifies Mitochondria as Therapeutic Targets of Multidrug-Resistance in Ovarian Cancer
por: Chen, Xiulan, et al.
Publicado: (2014)

Inorganic Nanocarriers Overcoming Multidrug Resistance for Cancer Theranostics
por: Lin, Gan, et al.
Publicado: (2016)

Stimuli-Responsive Nanomedicines for Overcoming Cancer Multidrug Resistance
por: Zhou, Lei, et al.
Publicado: (2018)

Synthesis and Anticancer Cytotoxicity of Azaaurones Overcoming Multidrug Resistance
por: Tóth, Szilárd, et al.
Publicado: (2020)

Overcoming Multidrug Resistance of Antibiotics via Nanodelivery Systems
por: Imran, Mohammad, et al.
Publicado: (2022)

Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells
por: Zhang, Jinming, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_of0plbavf0dvgalvt5t5h9itqn