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Cyclodextrin/chitosan nanoparticles for oral ovalbumin delivery: Preparation, characterization and intestinal mucosal immunity in mice

A novel oral protein delivery system with enhanced intestinal penetration and improved antigen stability based on chitosan (CS) nanoparticles and antigen-cyclodextrin (CD) inclusion complex was prepared by a precipitation/coacervation method. Ovalbumin (OVA) as a model antigen was firstly encapsulat...

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Detalles Bibliográficos
Autores principales: He, Muye, Zhong, Chen, Hu, Huibing, Jin, Yu, Chen, Yanzuo, Lou, Kaiyan, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032233/
https://www.ncbi.nlm.nih.gov/pubmed/32104451
http://dx.doi.org/10.1016/j.ajps.2018.04.001