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Succinylated whey protein isolate as a sustained-release excipient of puerarin derivative oral tablets: Preparation, optimization and pharmacokinetics

This work was done to investigate succinylated commercial whey protein isolate (S-WPI) as an oral sustained-release delivery carrier for puerarin 5 (PR-5). The succinylation conditions were established for S-WPIs by optimization of single factor study and Box–Beehnken design. The effect of succinyla...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Zhang, Yu, Wu, Yue, Liu, Jun, Ye, Tiantian, Wang, Shujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032234/
https://www.ncbi.nlm.nih.gov/pubmed/32104412
http://dx.doi.org/10.1016/j.ajps.2018.04.003