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Succinylated whey protein isolate as a sustained-release excipient of puerarin derivative oral tablets: Preparation, optimization and pharmacokinetics
This work was done to investigate succinylated commercial whey protein isolate (S-WPI) as an oral sustained-release delivery carrier for puerarin 5 (PR-5). The succinylation conditions were established for S-WPIs by optimization of single factor study and Box–Beehnken design. The effect of succinyla...
Autores principales: | Zhang, Rui, Zhang, Yu, Wu, Yue, Liu, Jun, Ye, Tiantian, Wang, Shujun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shenyang Pharmaceutical University
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032234/ https://www.ncbi.nlm.nih.gov/pubmed/32104412 http://dx.doi.org/10.1016/j.ajps.2018.04.003 |
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