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Model evaluation for the prediction of solubility of active pharmaceutical ingredients (APIs) to guide solid–liquid separator design

The assumptions and models for solubility modelling or prediction in systems using non-polar solvents, or water and complex triterpene and other active pharmaceutical ingredients as solutes aren't well studied. Furthermore, the assumptions concerning heat capacity effects (negligibility, experi...

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Detalles Bibliográficos
Autores principales: Moodley, Kuveneshan, Rarey, Jürgen, Ramjugernath, Deresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032238/
https://www.ncbi.nlm.nih.gov/pubmed/32104400
http://dx.doi.org/10.1016/j.ajps.2017.12.004