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Preparation and in vitro evaluation of an acidic environment-responsive liposome for paclitaxel tumor targeting

Paclitaxel (PTX) is an important cancer chemotherapeutic drug. To ameliorate the disadvantages of paclitaxel, this study designed liposomes to load paclitaxel, adding the acid-sensitive material cholesteryl hemisuccinate (CHEMS) to increase the accumulation of the drug in the tumor site. To begin, w...

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Detalles Bibliográficos
Autor principal: Wang, Lianqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032246/
https://www.ncbi.nlm.nih.gov/pubmed/32104360
http://dx.doi.org/10.1016/j.ajps.2017.05.008