Ginsenoside Rg1 Inhibits Cell Proliferation and Induces Markers of Cell Senescence in CD34+CD38− Leukemia Stem Cells Derived from KG1α Acute Myeloid Leukemia Cells by Activating the Sirtuin 1 (SIRT1)/Tuberous Sclerosis Complex 2 (TSC2) Signaling Pathway

BACKGROUND: Clinical relapse in acute myeloid leukemia (AML) is associated with the reduced treatment response of leukemia stem cells (LSCs). This study aimed to investigate the effects of the ginseng derivative, ginsenoside Rg1 (Rg1), on CD34+CD38− LSCs derived from KG1α human acute myeloid leukemi...

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Detalles Bibliográficos
Autores principales: Tang, Yan-Long, Zhang, Cheng-Gui, Liu, Heng, Zhou, Yue, Wang, Ya-Ping, Li, Yuan, Han, Yan-Jun, Wang, Cui-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032532/
https://www.ncbi.nlm.nih.gov/pubmed/32037392
http://dx.doi.org/10.12659/MSM.918207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032532/
https://www.ncbi.nlm.nih.gov/pubmed/32037392
http://dx.doi.org/10.12659/MSM.918207

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