Transglutaminase 2 mediates hypoxia-induced selective mRNA translation via polyamination of 4EBPs

Hypoxia selectively enhances mRNA translation despite suppressed mammalian target of rapamycin complex 1 activity, contributing to gene expression reprogramming that promotes metastasis and survival of cancer cells. Little is known about how this paradoxical control of translation occurs. Here, we r...

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Detalles Bibliográficos
Autores principales: Cho, Sung-Yup, Lee, Seungun, Yeom, Jeonghun, Kim, Hyo-Jun, Lee, Jin-Haeng, Shin, Ji-Woong, Kwon, Mee-ae, Lee, Ki Baek, Jeong, Eui Man, Ahn, Hee Sung, Shin, Dong-Myung, Kim, Kyunggon, Kim, In-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032569/
https://www.ncbi.nlm.nih.gov/pubmed/32075852
http://dx.doi.org/10.26508/lsa.201900565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032569/
https://www.ncbi.nlm.nih.gov/pubmed/32075852
http://dx.doi.org/10.26508/lsa.201900565

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