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Comparison of sequencing methods and data processing pipelines for whole genome sequencing and minority single nucleotide variant (mSNV) analysis during an influenza A/H5N8 outbreak

As high-throughput sequencing technologies are becoming more widely adopted for analysing pathogens in disease outbreaks there needs to be assurance that the different sequencing technologies and approaches to data analysis will yield reliable and comparable results. Conversely, understanding where...

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Detalles Bibliográficos
Autores principales: Poen, Marjolein J., Pohlmann, Anne, Amid, Clara, Bestebroer, Theo M., Brookes, Sharon M., Brown, Ian H., Everett, Helen, Schapendonk, Claudia M. E., Scheuer, Rachel D., Smits, Saskia L., Beer, Martin, Fouchier, Ron A. M., Ellis, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032710/
https://www.ncbi.nlm.nih.gov/pubmed/32078666
http://dx.doi.org/10.1371/journal.pone.0229326