GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior

The GluD1 gene is associated with susceptibility for schizophrenia, autism, depression, and bipolar disorder. However, the function of GluD1 and how it is involved in these conditions remain elusive. In this study, we generated a Grid1 gene-knockout (GluD1-KO) mouse line with a pure C57BL/6N genetic...

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Detalles Bibliográficos
Autores principales: Nakamoto, Chihiro, Kawamura, Meiko, Nakatsukasa, Ena, Natsume, Rie, Takao, Keizo, Watanabe, Masahiko, Abe, Manabu, Takeuchi, Tomonori, Sakimura, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032715/
https://www.ncbi.nlm.nih.gov/pubmed/32078638
http://dx.doi.org/10.1371/journal.pone.0229288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032715/
https://www.ncbi.nlm.nih.gov/pubmed/32078638
http://dx.doi.org/10.1371/journal.pone.0229288

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