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GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior
The GluD1 gene is associated with susceptibility for schizophrenia, autism, depression, and bipolar disorder. However, the function of GluD1 and how it is involved in these conditions remain elusive. In this study, we generated a Grid1 gene-knockout (GluD1-KO) mouse line with a pure C57BL/6N genetic...
Autores principales: | Nakamoto, Chihiro, Kawamura, Meiko, Nakatsukasa, Ena, Natsume, Rie, Takao, Keizo, Watanabe, Masahiko, Abe, Manabu, Takeuchi, Tomonori, Sakimura, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032715/ https://www.ncbi.nlm.nih.gov/pubmed/32078638 http://dx.doi.org/10.1371/journal.pone.0229288 |
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