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Hantavirus inhibits apoptosis by preventing mitochondrial membrane potential loss through up-regulation of the pro-survival factor BCL-2

Hantaviruses, zoonotic RNA viruses belonging to the order Bunyavirales, cause two severe acute diseases in humans, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Hantavirus-infected patients show strong cytotoxic lymphocyte responses and hyperinflammation; howe...

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Detalles Bibliográficos
Autores principales: Solà-Riera, Carles, García, Marina, Ljunggren, Hans-Gustaf, Klingström, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032725/
https://www.ncbi.nlm.nih.gov/pubmed/32032391
http://dx.doi.org/10.1371/journal.ppat.1008297