Cargando…
Performance of a mixture model by the degree of a missing categorical covariate when estimating clearance in NONMEM
The accuracy and predictability of mixture models in NONMEM® may change depending on the relative size of inter-individual differences and the size of the differences in the parameters between subpopulations. This study explored the accuracy of mixture models when dealing with missing a categorical...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society for Clinical Pharmacology and Therapeutics
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032962/ https://www.ncbi.nlm.nih.gov/pubmed/32095482 http://dx.doi.org/10.12793/tcp.2019.27.4.141 |