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Performance of a mixture model by the degree of a missing categorical covariate when estimating clearance in NONMEM

The accuracy and predictability of mixture models in NONMEM® may change depending on the relative size of inter-individual differences and the size of the differences in the parameters between subpopulations. This study explored the accuracy of mixture models when dealing with missing a categorical...

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Detalles Bibliográficos
Autores principales: Yoon, SeokKyu, Lim, Hyeong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032962/
https://www.ncbi.nlm.nih.gov/pubmed/32095482
http://dx.doi.org/10.12793/tcp.2019.27.4.141

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