Cargando…

Inhibition of Na(V)1.8 prevents atrial arrhythmogenesis in human and mice

Pharmacologic approaches for the treatment of atrial arrhythmias are limited due to side effects and low efficacy. Thus, the identification of new antiarrhythmic targets is of clinical interest. Recent genome studies suggested an involvement of SCN10A sodium channels (Na(V)1.8) in atrial electrophys...

Descripción completa

Detalles Bibliográficos
Autores principales: Pabel, Steffen, Ahmad, Shakil, Tirilomis, Petros, Stehle, Thea, Mustroph, Julian, Knierim, Maria, Dybkova, Nataliya, Bengel, Philipp, Holzamer, Andreas, Hilker, Michael, Streckfuss-Bömeke, Katrin, Hasenfuss, Gerd, Maier, Lars S., Sossalla, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033079/
https://www.ncbi.nlm.nih.gov/pubmed/32078054
http://dx.doi.org/10.1007/s00395-020-0780-8