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Tracing tumorigenesis in a solid tumor model at single-cell resolution

Characterizing the complex composition of solid tumors is fundamental for understanding tumor initiation, progression and metastasis. While patient-derived samples provide valuable insight, they are heterogeneous on multiple molecular levels, and often originate from advanced tumor stages. Here, we...

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Detalles Bibliográficos
Autores principales: Praktiknjo, Samantha D., Obermayer, Benedikt, Zhu, Qionghua, Fang, Liang, Liu, Haiyue, Quinn, Hazel, Stoeckius, Marlon, Kocks, Christine, Birchmeier, Walter, Rajewsky, Nikolaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033116/
https://www.ncbi.nlm.nih.gov/pubmed/32080185
http://dx.doi.org/10.1038/s41467-020-14777-0