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Jouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila

Longevity is influenced by genetic and environmental factors, but the underlying mechanisms remain elusive. Here, we functionally characterise a Drosophila small nucleolar RNA (snoRNA), named jouvence whose loss of function reduces lifespan. The genomic region of jouvence rescues the longevity in mu...

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Detalles Bibliográficos
Autores principales: Soulé, Stéphanie, Mellottée, Lucille, Arab, Abdelkrim, Chen, Chongjian, Martin, Jean-René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033134/
https://www.ncbi.nlm.nih.gov/pubmed/32080190
http://dx.doi.org/10.1038/s41467-020-14784-1