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IgG-Fc glycosylation before and after rituximab treatment in immune thrombocytopenia

The interactions of antibodies with myeloid Fcγ receptors and the complement system are regulated by an Asn297-linked glycan in the Fc portion of IgG. Alterations of serum IgG-Fc glycosylation have been reported in various autoimmune diseases, and correlate with treatment response and disease activi...

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Detalles Bibliográficos
Autores principales: Schmidt, David E., de Haan, Noortje, Sonneveld, Myrthe E., Porcelijn, Leendert, van der Schoot, C. Ellen, de Haas, Masja, Zwaginga, Jaap-Jan, Wuhrer, Manfred, Vidarsson, Gestur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033207/
https://www.ncbi.nlm.nih.gov/pubmed/32080262
http://dx.doi.org/10.1038/s41598-020-59651-7