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IgG-Fc glycosylation before and after rituximab treatment in immune thrombocytopenia
The interactions of antibodies with myeloid Fcγ receptors and the complement system are regulated by an Asn297-linked glycan in the Fc portion of IgG. Alterations of serum IgG-Fc glycosylation have been reported in various autoimmune diseases, and correlate with treatment response and disease activi...
Autores principales: | Schmidt, David E., de Haan, Noortje, Sonneveld, Myrthe E., Porcelijn, Leendert, van der Schoot, C. Ellen, de Haas, Masja, Zwaginga, Jaap-Jan, Wuhrer, Manfred, Vidarsson, Gestur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033207/ https://www.ncbi.nlm.nih.gov/pubmed/32080262 http://dx.doi.org/10.1038/s41598-020-59651-7 |
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