Mid age APOE ε4 carriers show memory-related functional differences and disrupted structure-function relationships in hippocampal regions

Carriers of the APOE e4 allele are at higher risk of age-related cognitive decline and Alzheimer’s disease (AD). The underlying neural mechanisms are uncertain, but genotype differences in medial temporal lobe (MTL) functional activity and structure at mid-age might contribute. We tested 16 non-e4 a...

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Detalles Bibliográficos
Autores principales: Evans, Simon L., Dowell, Nicholas G., Prowse, Fenella, Tabet, Naji, King, Sarah L., Rusted, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033211/
https://www.ncbi.nlm.nih.gov/pubmed/32080211
http://dx.doi.org/10.1038/s41598-020-59272-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033211/
https://www.ncbi.nlm.nih.gov/pubmed/32080211
http://dx.doi.org/10.1038/s41598-020-59272-0

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