Intestinal Alkaline Phosphatase Exerts Anti-Inflammatory Effects Against Lipopolysaccharide by Inducing Autophagy

Intestinal alkaline phosphatase (IAP) regulates bicarbonate secretion, detoxifies lipopolysaccharide (LPS), regulates gut microbes, and dephosphorylates proinflammatory nucleotides. IAP also exhibits anti-inflammatory effects in a Toll-like Receptor-4 (TLR-4) dependent manner. However, it is not kno...

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Detalles Bibliográficos
Autores principales: Singh, Sudha B., Carroll-Portillo, Amanda, Coffman, Cristina, Ritz, Nathaniel L., Lin, Henry C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033233/
https://www.ncbi.nlm.nih.gov/pubmed/32080230
http://dx.doi.org/10.1038/s41598-020-59474-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033233/
https://www.ncbi.nlm.nih.gov/pubmed/32080230
http://dx.doi.org/10.1038/s41598-020-59474-6

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