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A semi-automated technique for adenoma quantification in the Apc(Min) mouse using FeatureCounter

Colorectal cancer is a major contributor to death and disease worldwide. The Apc(Min) mouse is a widely used model of intestinal neoplasia, as it carries a mutation also found in human colorectal cancers. However, the method most commonly used to quantify tumour burden in these mice is manual adenom...

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Detalles Bibliográficos
Autores principales: Shepherd, Amy L., Smith, A. Alexander T., Wakelin, Kirsty A., Kuhn, Sabine, Yang, Jianping, Eccles, David A., Ronchese, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033248/
https://www.ncbi.nlm.nih.gov/pubmed/32080295
http://dx.doi.org/10.1038/s41598-020-60020-7