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H-Ferritin is essential for macrophages’ capacity to store or detoxify exogenously added iron

Macrophages are central cells both in the immune response and in iron homeostasis. Iron is both essential and potentially toxic. Therefore, iron acquisition, transport, storage, and release are tightly regulated, by several important proteins. Cytosolic ferritin is an iron storage protein composed o...

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Detalles Bibliográficos
Autores principales: Mesquita, Gonçalo, Silva, Tânia, Gomes, Ana C., Oliveira, Pedro F., Alves, Marco G., Fernandes, Rui, Almeida, Agostinho A., Moreira, Ana C., Gomes, Maria Salomé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033252/
https://www.ncbi.nlm.nih.gov/pubmed/32080266
http://dx.doi.org/10.1038/s41598-020-59898-0