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H-Ferritin is essential for macrophages’ capacity to store or detoxify exogenously added iron
Macrophages are central cells both in the immune response and in iron homeostasis. Iron is both essential and potentially toxic. Therefore, iron acquisition, transport, storage, and release are tightly regulated, by several important proteins. Cytosolic ferritin is an iron storage protein composed o...
Autores principales: | Mesquita, Gonçalo, Silva, Tânia, Gomes, Ana C., Oliveira, Pedro F., Alves, Marco G., Fernandes, Rui, Almeida, Agostinho A., Moreira, Ana C., Gomes, Maria Salomé |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033252/ https://www.ncbi.nlm.nih.gov/pubmed/32080266 http://dx.doi.org/10.1038/s41598-020-59898-0 |
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