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Slc20a1/Pit1 and Slc20a2/Pit2 are essential for normal skeletal myofiber function and survival

Low blood phosphate (Pi) reduces muscle function in hypophosphatemic disorders. Which Pi transporters are required and whether hormonal changes due to hypophosphatemia contribute to muscle function is unknown. To address these questions we generated a series of conditional knockout mice lacking one...

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Detalles Bibliográficos
Autores principales: Chande, Sampada, Caballero, Daniel, Ho, Bryan B., Fetene, Jonathan, Serna, Juan, Pesta, Dominik, Nasiri, Ali, Jurczak, Michael, Chavkin, Nicholas W., Hernando, Nati, Giachelli, Cecilia M., Wagner, Carsten A., Zeiss, Caroline, Shulman, Gerald I., Bergwitz, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033257/
https://www.ncbi.nlm.nih.gov/pubmed/32080237
http://dx.doi.org/10.1038/s41598-020-59430-4