The Eaf3 chromodomain acts as a pH sensor for gene expression by altering its binding affinity for histone methylated-lysine residues

During gene expression, histone acetylation by histone acetyltransferase (HAT) loosens the chromatin structure around the promoter to allow RNA polymerase II (Pol II) to initiate transcription, while de-acetylation by histone deacetylase (HDAC) tightens the structure in the transcribing region to re...

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Detalles Bibliográficos
Autores principales: Okuda, Masahiko, Nishimura, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033311/
https://www.ncbi.nlm.nih.gov/pubmed/32031206
http://dx.doi.org/10.1042/BSR20191958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033311/
https://www.ncbi.nlm.nih.gov/pubmed/32031206
http://dx.doi.org/10.1042/BSR20191958

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